----- Original Message -----
From: Jerry Wayne Decker <jwdatwork@yahoo.com>
To: <interact@keelynet.com>
Sent: donderdag 16 september 1999 23:44
Subject: Heart attacks & blood flow
> Hi Folks!
>
> A friend's mother recently went into the hospital from
> a heart attack so I was telling her about some useful
> info that MIGHT be of interest;
>
> Linus Paulings' patented discovery that you can do for
> yourself...if the pharmaceutical companies can't make
> money from it, you won't hear about it, as much detail
> as we have is here;
>
> http://www.keelynet.com/biology/plaque.htm
>
> This is claimed to be a means to thin the blood and
> keep the arteries clean;
>
> http://www.keelynet.com/biology/heartcur.txt
>
> and here is a repost that I couldn't get the URL to
> work on so I'm having to quote the article;
>
> http://www2.beverageonline.com/welcome/ngck
>
> Circulation Article Reports Ways Purple Grape Juice
> may Fight Narrowing of the Arteries
>
> - Clinician Cites Effect of the Juice in Study on
> Contributors to Coronary Artery Disease --
>
> CONCORD, Mass., Sept. 7 /PRNewswire/ -- Researchers
> from the University of Wisconsin Medical School have
> identified ways in which drinking purple grape juice
> may fight atherosclerosis, or narrowing of the
> arteries, according to a study in the September 7th
> issue of Circulation, a journal published by the
> American Heart Association.
>
> The study showed that when fifteen subjects, all
> people with coronary artery disease, drank purple
> grape juice for two weeks, the elasticity of their
> blood vessels significantly increased and the rate at
> which their LDL cholesterol oxidized significantly
> decreased.
>
> 'This is of great interest,' notes John Folts, Ph.D.,
> 'because it suggests that consuming purple grape juice
> could positively effect the atherosclerotic process in
> several important ways. Previously, much of the
> potential benefit of consuming purple grape juice was
> attributed to its apparent ability to make the blood
> less likely to clot. Now we see that there appear to
> be two other beneficial factors at work as well.'
>
> Dr. Folts, the senior author of the study and director
> of the Coronary Thrombosis Research and Prevention
> Laboratory at the University of Wisconsin Medical
> School, has conducted extensive research in this area,
> with much of his previous work focusing on the ability
> of grape products to reduce the stickiness of blood
> platelets.
>
> 'There are a number of primary contributors to
> atherosclerosis,' explains Folts, 'Three of them are
> the stickiness of our blood, the reduced flexibility
> of our arteries, and the speed at which we oxidize LDL
> cholesterol. In previous studies, we saw that
> drinking purple grape juice reduced blood stickiness.
> What this study suggests is that drinking the juice
> has a beneficial effect on two other primary
> contributors as well.'
>
> Vasodilation
>
> The ability of the blood vessels to expand in response
> to increased blood flow and thus deliver more oxygen
> where it's needed is called flow-mediated
> vasodilation.
> It is indicative of the health of the endothelium --
> the layer of cells which lines the interior wall of
> all the blood vessels in the body. When the
> endothelium is impaired, such as in people with
> existing coronary artery disease, blood vessels are
> less able to respond to the sudden need for increased
> blood flow. They are also more susceptible to
> atherosclerosis, or narrowing of the arteries, and
> blood clot formation.
>
> When blood clots in a narrowed artery, a heart attack
> or stroke may occur.
>
> People with existing coronary artery disease typically
> have impaired endothelial function.
>
> The study looked at fifteen men and women (average age
> 62.5 plus or minus 12.7) with coronary artery disease.
>
> Each person drank approximately 7 cc/kg/day of the
> juice for 14 days. Flow mediated vasodilation -- the
> ability of the arteries to expand in response to
> increased flow of blood -- was measured at baseline as
> 2.2mm plus or minus 2.9%.
>
> After the juice was consumed for 14 days, flow
> mediated dilation was measured again and found to be
> 6.4mm plus or minus 4.7% (p= 0.003), resulting in a
> mean change of 4.2mm plus or minus 2.9% (p<0.001) --
> almost triple the previous ability of the blood
> vessels to respond to increased blood flow.
>
> LDL Oxidation Rates
>
> In studying LDL oxidation, blood samples were drawn
> and LDL oxidation lag time was measured for each
> subject at the beginning of the study and then again
> at its conclusion. Lag time measurement is a commonly
> used method for determining how long it takes for
> cholesterol to oxidize when exposed to certain oxidant
> chemicals.
>
> The longer the lag time, the slower the onset of LDL
> oxidation. The slower the onset of oxidation, the less
> likely that oxidation will contribute to
> atherosclerosis, since oxidized cholesterol
> contributes to the build-up of plaque in the arteries.
>
> Among the entire group, the lag time improved by 34.5%
> (p= 0.015). At the beginning of the study the average
> lag time was 87 minutes (plus or minus 29 minutes).
>
> After the juice was consumed for 14 days, lag time was
> measured again. After the juice, average lag time
> improved to 117 minutes (plus or minus 23 minutes).
>
> Eleven patients in the study were consuming vitamin E
> (400IU/day). For them, the initial lag time was 86
> minutes (plus or minus 33 minutes); after drinking the
> juice it improved to 121 minutes (plus or minus 24
> minutes).
>
> 'People with excellent cardiovascular health usually
> have healthy endothelial function, a slow onset of LDL
> oxidation and moderate blood platelet activity,' notes
> Folts.
>
> 'This study suggests that drinking purple grape juice
> may promote these heart healthy mechanisms. Combined
> with what we have learned from previous studies on
> grape juice's ability to decrease platelet activity,
> it makes sense to include daily consumption of purple
> grape juice as part of a diet high in fruits and
> vegetables and low in saturated fat.'
>
> Welch's Purple 100% Grape Juice has been certified by
> the American Heart Association for its HeartCheck
> program. The study was underwritten, in part, by the
> Oscar Rennenbohm Foundation, Madison, WI; the Nutricia
> Research Foundation, The Netherlands; and Welch Foods
> Inc., A Cooperative, Concord, MA.
>
> ===
>
>
> =================================
> Please respond to jdecker@keelynet.com
> as I am writing from my work email of
> jwdatwork@yahoo.com.........thanks!
> =================================
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