Anaphylaxis and vaccination
Vaccine ingredients   Citations

Anaphylactic shock (anaphylaxis). An immediate (type 1) hypersensitivity reaction. Acute, often explosive, allergic systemic reaction, characterized by circulatory failure (e.g. alteration of level of consciousness, low arterial blood pressure, weakness or absence of peripheral pulses, cold extremities secondary to reduced peripheral circulation, flushed face and increased perspiration) with or without bronchospasm and/or laryngospasm/laryngeal oedema leading to respiratory distress. May also include pruritis, generalized flushes, angioedema (hives), seizures, vomiting, abdominal cramps and incontinence. It occurs in previously sensitized persons who receive the sensitizing antigens again. Supplementary information on vaccine safety WHO/V&B/00

[2009 Nov] PHAC confirms 24 cases of anaphylaxis across Canada after H1N1 flu shots  There have been 24 confirmed cases of a type of severe allergic reaction called anaphylaxis in Canadians who have received an H1N1 flu shot, including one person who died after getting vaccinated, the head of the Public Health Agency of Canada said Wednesday.

[2009 Oct] Shock reaction sparks flu vaccine inquiry

[2008 Sept] HPV vaccine shows higher rate of anaphylaxis: study The human papilomavirus (HPV) vaccine is up to 20 times more likely than other school-based vaccines to cause anaphylaxis, according to a study released Monday.

[July 2006] Anaphylactic children - canaries in the public health mine shaft? Are vaccines responsible for the epidemic of anaphylaxis in young children today? by Rita Hoffman

The pertussis vaccine has been used in animal experiments to help produce anaphylactic shock, and to cause an acute autoimmune encephalomyelitis (allergic encephalitis).  Drs. Cherry, Brunell, et al., "Report of the Task Force on Pertussis and Pertussis Immunization," Pediatrics, 81:6, pt. 2 (June 1988), p. 943.
 
Aukrust L, et al.    Severe hypersensitivity or intolerance reactions to measles vaccine in six children. Clinical and immunological studies. Allergy. 1980 Oct;35(7):581-7. PMID: 7468944; UI: 81131462. 
Bilyk MA, et al. [See Related Articles] [Anaphylactic reaction following subcutaneous administration of tetanus anatoxin]. Klin Med (Mosk). 1978 Sep;56(9):137-8. Russian. No abstract available.PMID: 703231; UI: 79030708.
Davis WE, et al.      Anaphylaxis in immunotherapy. Otolaryngol Head Neck Surg. 1992 Jul;107(1):78-83. PMID: 1528607; UI: 92409226.    
Egorova, NB, "Anaphylactic Reaction And Anti-toxin Titre Following Aerosol and Subcutaneous Immunization Against Tetanus", Zh Mikrobiol, Apr 1968, 45:63-68.

James, LP, Jr, et al, "Fatal Systemic Anaphylaxis in man", NEJM, Mar 19, 1964; 270:597-603.

Kelleher, PC, et al, "Anaphylactoid Reaction After Typhoid Vaccination", Am J Med, Dec 1990, 89(6):822-824.

Koval’skala Sia, "Anaphylactogenic Properties of ADT, PDT, and APDT Vaccines...", Zh Mikrobiol, Jan 1969; 46:65-71.

Kelso JM, et al.   Anaphylaxis to measles, mumps, and rubella vaccine mediated by IgE to gelatin. J Allergy Clin Immunol. 1993 Apr;91(4):867-72. PMID: 8473675; UI: 93232477.

Kelso JM, et al.   Anaphylaxis from yellow fever vaccine. J Allergy Clin Immunol. 1999 Apr;103(4):698-701. PMID: 10200022; UI: 99216472.

Lear, J T, et al, "Anaphylaxis After Hepatitis B Vaccination", Lancet, May 13, 1995, 345(8959): 1249.

Leung AK, "Anaphylaxis to DPT vaccine." J R Soc Med 1985 Feb; 78(2):175.

Nazareth B, et al.     Systemic allergic reactions to Japanese encephalitis vaccines. Vaccine. 1994 May;12(7):666. No abstract available.PMID: 8085387; UI: 94367631   

NA, "Anaphylaxis Due to Vaccination in the Office", Can Med Assoc J, May 15, 1986, 134(10): 1109.

Ovens, H, "Anaphylaxis Due to Vaccination in the Office", Can Med Assoc J, Feb 15, 1986, 134(4):369-370.

Proctor, JW, et al, "Anaphylactoid Reaction to Intralesional BCG", Lancet, Jul 15, 1978, 2(8081):162.

Sakaguchi M, et al.   Food allergy to gelatin in children with systemic immediate-type reactions, including anaphylaxis, to vaccines. J Allergy Clin Immunol. 1996 Dec;98(6 Pt 1):1058-61. PMID: 8977505; UI: 97132048.

Spiess H, et al. [See Related Articles] [Anaphylactic reaction following active tetanus immunization]. Dtsch Med Wochenschr. 1973 Mar 20;98(13):682. German. No abstract available.PMID: 4696498; UI: 73154013.
Tilz GP, et al. [Anaphylactic reactions following vaccinations]. Dtsch Med Wochenschr. 1973 May 18;98(20):1047. German. No abstract available.PMID: 4707651; UI: 73186207[See Related Articles]

Thurston A.    Anaphylactic shock reaction to measles vaccine. J R Coll Gen Pract. 1987 Jan;37(294):41. No abstract available.PMID: 3668928; UI: 88035790.   

Thibodeau JL.     Office management of childhood vaccine-related anaphylaxis. Can Fam Physician. 1994 Sep;40:1602-10. Review. PMID: 7920053; UI: 95003795.   

Vollset P. [See Related Articles] [A case of anaphylactic shock following BCG vaccination]. Tidsskr Nor Laegeforen. 1965 May 15;85(10):850. Norwegian. No abstract available.PMID: 5863977; UI: 66099722.

Wiseman, "Anaphylactoid Reaction to Tetanus Toxoid", Ann Allerg, Nov 1982, 49(5):308.

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