Neuropathy & vaccination
Nervous system & vaccination
Blumstein GI, Kreithen H. Peripheral neuropathy following tetanus toxoid administration.JAMA. 1966 Nov 28;198(9):1030-1. No abstract available.PMID: 4288653 [PubMed - indexed for MEDLINE]
Baust W, Meyer D, Wachsmuth W. Peripheral neuropathy after administration of tetanus toxoid.J Neurol. 1979;222(2):131-33.PMID: 93631 [PubMed - indexed for MEDLINE]
Courrier
A, Stenbach G, Simonnet P, Rumilly P, Lopez D, Coquillat G, Scherer C, Chopin J.
Peripheral neuropathy following fetal bovine cell rabies vaccine.Lancet. 1986 May 31;1(8492):1273. No abstract available.PMID: 2872413 [PubMed -
indexed for MEDLINE]
We treated a patient who had a demyelinating peripheral neuropathy and a central nervous
system inflammatory demyelinating disease. The unusual pathologic feature of dense
infiltrates of atypical macrophages was observed in many areas of the brain; otherwise the
process had several features in common with either multiple sclerosis or chronic relapsing
experimental allergic encephalomyelitis. The illness followed "swine-flu"
inoculation; exacerbation followed pneumococcal vaccination.
Cusi MG, Bianchi S, Santini L, Donati D, Valassina M, Valensin PE, Cioe L, Mazzocchio R. Peripheral neuropathy associated with anti-myelin basic protein antibodies in a woman vaccinated with rubella virus vaccine.J Neurovirol. 1999 Apr;5(2):209-14.PMID: 10321986 [PubMed - indexed for MEDLINE]
Ducloux M, Robin Y, Chaffaut A. [A further case of neuropathy following rabies vaccination]Bull Soc Med Afr Noire Lang Fr. 1974;19(3):247-50. French. No abstract available.PMID: 4457252 [PubMed - indexed for MEDLINE]
Dyro FM. Vaccination mononeuropathy. Ann Neurol. 1978 May;3(5):468. No abstract available.PMID: 215078; UI: 79081241. Felix JK, et al. Isolated hypoglossal nerve paralysis following influenza vaccination. Am J Dis Child. 1976 Jan;130(1):82-3.Holliday PL, Bauer RB. Polyradiculoneuritis secondary to immunization with tetanus and diphtheria toxoids.Arch Neurol. 1983 Jan;40(1):56-7. No abstract available.PMID: 6848095 [PubMed - indexed for MEDLINE]
Hasselbacher P. Neuropathy after influenza vaccination [letter]. Lancet. 1977 Mar 5;1(8010):551-2. No abstract available.PMID: 65654; UI: 77122811.
Paradiso, G et al, "Multifocal Demyelinating Neuropathy after Tetanus Vaccine", Medicina (B Aires), 1990, 50 (1):52-54.
Powell
HC, Mizisin AP, Wiley CA, Morey MK, Hughes RA. Relationship of
adjuvants and swine influenza vaccine to experimental neuropathy in rabbits.Acta Neuropathol (Berl). 1987;73(1):12-8.PMID: 3037840 [PubMed - indexed for
MEDLINE]
Experimental neuropathy, characterized by endoneurial edema and demyelination, was induced
by inoculating rabbits with a combination of Freund's complete adjuvant (FCA),
gangliosides, lecithin and cholesterol. A less severe demyelinating neuropathy could be
induced by treatment with FCA alone but no significant change could be elicited by
injection of swine influenza vaccine (SFV) alone. When FCA was combined with gangliosides,
lecithins, cholesterol and SFV, neuropathy occurred, but the changes were less severe than
if these agents were used without SFV. Sera were tested for myelin basic protein (MBP) and
galactocerebroside (GC) antibodies in each experimental group. Neither SFV alone nor SFV
combined with Freund's complete adjuvant, gangliosides, cholesterol and lecithin evoked
significant antibody titers to MBP or GC. However, rabbits inoculated with FCA,
gangliosides, lecithin and cholesterol had rising titers of antibody to both MBP and GC
over the 3-month experimental period. One rabbit inoculated with FCA alone had significant
antibody to MBP. The findings suggest that Freund's complete adjuvant alone can induce
demyelination in the peripheral nerves of rabbits and that SFV may modulate the immune
response acting either as an adjuvant or suppressant in the experimental demyelinating
disease.
Reinstein
L, Pargament JM, Goodman JS. Peripheral neuropathy after multiple
tetanus toxoid injections. Arch Phys Med Rehabil. 1982
Jul;63(7):332-4. PMID: 6284088 [PubMed - indexed for MEDLINE]
This case documents the 14th reported patient with peripheral neuropathy
following tetanus toxoid injection. A 33-year-old man developed profound mixed
sensorimotor peripheral neuropathy after receiving 2 tetanus toxoid injections over a
5-month period. Periodic serial electromyographic and nerve conduction studies performed
over 2 years suggested both segmental demyelination and axonal neuropathy. The patient
experienced partial recovery. Analysis of this case and 13 others reported in literature
indicates that in almost all cases (85%), patients had received multiple tetanus toxoid
injections. Also, it appears that a prolonged interval of 14 or more days between the
tetanus toxoid injection and the onset of neurological symptoms is associated with a
poorer prognosis for complete recovery.
Sander
D, et al. Postvaccinal plexus neuropathy following vaccination against
tick-borne encephalitis and tetanus in a competitive athlete. Clin Investig. 1994
May;72(5):399. No abstract available.PMID: 8086776; UI: 94369223.
Scholz
E, et al. [Postvaccinal neuritis following prophylactic vaccination
against early-summer meningo-encephalitis]. Dtsch Med Wochenschr. 1987 Apr
3;112(14):544-6. German. PMID: 3829935; UI: 87161333.
Wilmshurst
JM, Macleod MJ, Hughes E, Hughes RA. Acute sensory neuropathy in
an adolescent girl following BCG vaccination. Europ J Paediatr
Neurol. 1999;3(6):277-9. PMID: 10595673 [PubMed - indexed for MEDLINE]
A 13-year-old girl developed a sensory neuropathy following bacille
Calmette-Guerin (BCG) vaccination, consistent with acute inflammatory demyelinating
polyradiculoneuropathy or acute sensory axonal neuropathy.