http://www.thememoryhole.org/health/fluoride-patent.htm

>>> From Patent #5,807,541 "NSAID/fluoride periodontal compositions and methods" (15 Sept 1998), filed by the pharmaceutical company Sepracor:

A method for preventing dental caries [cavities] by administering fluoride and, at the same time controlling periodontal bone loss precipitated by the fluoride, by providing a combination of fluoride and NSAID is disclosed.

...

We have found that fluoride, in the concentration range in which it is employed for the prevention of dental caries [cavities], stimulates the production of prostaglandins and thereby exacerbates the inflammatory response in gingivitis and periodontitis.

...

Thus, the inclusion of fluoride in toothpastes and mouthwashes for the purpose of inhibiting the development of caries [cavities] may, at the same time, accelerate the process of chronic, destructive periodontitis.

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