Nervous system disease & vaccination
Vaccine diseases  Citations

David A Geier, Mark R Geier MD PhD. Chronic adverse reactions associated with hepatitis B vaccination The Annals of Pharmacotherapy 2002: Vol. 36, No. 12, pp. 1970–1971.
In conclusion, our study demonstrates that adult HBV is statistically associated not only with acute neuropathy, neuritis, myelitis, vasculitis, thrombocytopenia, gastrointestinal disease, multiple sclerosis, and arthritis, but some of these patients go on to develop chronic adverse reactions that persist for at least 1 year following HBV. These types of chronic adverse reactions following adult HBV should be discussed with patients contemplating being immunized with HBV and should be included in the differential diagnosis of those who develop them following adult HBV.

Tornatore CS, Richert JR. CNS demyelination associated with diploid cell rabies vaccine. Lancet. 1990 Jun 2;335(8701):1346-7. No abstract available. PMID: 1971408 [PubMed - indexed for MEDLINE]

Ehrengut, W et al, "On Convulsive Reactions Following Oral vaccination Against Polio", Klin Paediatr, May 1979, 191(3):261-270.

Vaccinations and Unexplained Diseases:

Hiner, E E, Frasch, C E, "Spectrum of Disease Due to Haemophilus Influenza Type B Occurring in Vaccinated Children", J Infect Disorder, 1988 Aug; 158(2): 343-348.

Vadheim, CM, et al, "Effectiveness and Safety of an Haemophilus Influenzae type b Conjugate Vaccine (PRP-T) in Young Infants. Kaiser-UCLA Vaccine Study Group," Pediartics, 1993 Aug; 92(2):272-279. [The vaccines caused fevers, irritability, crying, and seizures, but were declared to be "safe and ... effective ... ".]

Stickl, H, "Estimation of Vaccination Damage", Med Welt, Oct 14, 1972, 23:1495-1497.

Waters, VV, et al, "Risk Factors for Measles in a Vaccinated Population", JAMA, Mar 27, 1991, 265(12): 1527.

Stickl, H, "Iatrogenic Immuno-suppression as a Result of Vaccination", Fortschr Med, Mar 5, 1981, 99(9);289-292.

Dyro FM. Vaccination mononeuropathy.Ann Neurol. 1978 May;3(5):468. No abstract available.PMID: 215078 [PubMed - indexed for MEDLINE]

Maillefert JF, Farge P, Gazet-Maillefert MP, Tavernier C.  Mental nerve neuropathy as a result of hepatitis B vaccination.Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997 Jun;83(6):663-4.PMID: 9195619 [PubMed - indexed for MEDLINE]

Powell HC, Mizisin AP, Wiley CA, Morey MK, Hughes RA.  Relationship of adjuvants and swine influenza vaccine to experimental neuropathy in rabbits.Acta Neuropathol (Berl). 1987;73(1):12-8.PMID: 3037840 [PubMed - indexed for MEDLINE]
Experimental neuropathy, characterized by endoneurial edema and demyelination, was induced by inoculating rabbits with a combination of Freund's complete adjuvant (FCA), gangliosides, lecithin and cholesterol. A less severe demyelinating neuropathy could be induced by treatment with FCA alone but no significant change could be elicited by injection of swine influenza vaccine (SFV) alone. When FCA was combined with gangliosides, lecithins, cholesterol and SFV, neuropathy occurred, but the changes were less severe than if these agents were used without SFV. Sera were tested for myelin basic protein (MBP) and galactocerebroside (GC) antibodies in each experimental group. Neither SFV alone nor SFV combined with Freund's complete adjuvant, gangliosides, cholesterol and lecithin evoked significant antibody titers to MBP or GC. However, rabbits inoculated with FCA, gangliosides, lecithin and cholesterol had rising titers of antibody to both MBP and GC over the 3-month experimental period. One rabbit inoculated with FCA alone had significant antibody to MBP. The findings suggest that Freund's complete adjuvant alone can induce demyelination in the peripheral nerves of rabbits and that SFV may modulate the immune response acting either as an adjuvant or suppressant in the experimental demyelinating disease.