Pineal-hypothalamic tract mediation of picotesla magnetic fields
in the treatment of neurological disorders.
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Jacobson JI
Institute of Theoretical Physics and Advanced Studies for
Biophysical Research, Jupiter, FL 334377-1418, USA.
Panminerva Med, 36:201-5, 1994 Dec
The objective of this study is analysis of the clinical efficacy of
picotesla magnetic fields in the treatment of epilepsy, Parkinson's
disease and multiple sclerosis. The method utilized involved the
exogenous application of physiologic, very weak magnetic fields to
the brain by Sandyk, Anninos, Derpapas and Tsagas. The magnetic
device produced a magnetic field ranging from about 5 x 10(-8)
gauss to about 2.5 x 10(-7) gauss at frequencies of 2 to 7 Hertz.
The wave form was sinusoidal and the device was positioned about
the posterior portion of the corpus callosum most specifically to
influence the pineal gland.
........
External magnetic fields have been found to synchronise Melatonin
secretion in experimental animals and humans and may be beneficial
in the treatment of postmenopausal osteoporosis. Pineal Melatonin
has been shown in animals to be involved in the regulation of
calcium and phosphorus metabolism by stimulating the parathyroid
glands and by inhibiting calcitonin release and prostaglandin
synthesis. The menopause is associated with a decline in
Melatonin secretion and increased pineal calcification.
--Sandyk R, Neuroscience 62(3-4):215-25, 1992 February
........
Dysfunction of pineal melatonin releases in humans has been
associated with the pathophysiology of depression and
schizophrenia, among other unwanted conditions. And recently,
patients with coronary heart disease were found to have impaired
nocturnal melatonin secretion because of their increased
nocturnal noradrenaline.
The pineal gland may function as a fine tuner of calcium
homeostasis; the fall of melatonin plasma levels during the early
stage of menopause may be an important contributory factor in the
development of postmenopausal osteoporosis. Light therapy,
administration of oral melatonin (2.5 mg at night) or agents
which induce a sustained release of melatonin secretion such as
5-methoxypsoralen, could be useful agents in the prophylaxis and
treatment of postmenopausal osteoporosis. Treatment with
appropriate artificial magnetic fields may also be beneficial
for postmenopausal osteoporosis.
........
Magnetic stimulation in the treatment of partial seizures.
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Anninos PA; Tsagas N; Sandyk R; Derpapas K
Democrition University of Thrace, Department of Medical Physics
and Polytechnic School, Alexandroupolis, Greece.
Int J Neurosci, 60:141-71, 1991 Oct
[....] Specifically, since the pineal gland has been shown to be a
magnetosensitive organ which forms part of a combined compass-solar
clock system, and since it exerts an inhibitory action on seizure
activity in both experimental animals and humans, we discuss the
potential pivotal role of the pineal gland in the long term
anticonvulsant effects of external artificial magnetic stimulation.
........
Treatment with weak electromagnetic fields
restores dream recall in a Parkinsonian patient.
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Sandyk R
Department of Neuroscience, Institute for Biomedical Engineering
& Rehabilitation Services, Touro College, Dix Hills, NY 11746, USA
Int J Neurosci 1997 Jun;90(1-2):75-86
[....] Moreover, since DA (dopamine) neurons activate REM sleep
mechanisms and facilitate dream recall, it appears that
application of EMFs enhanced DA activity in the mesolimbic
system which has been implicated in dream recall. Also, since
administration of pineal melatonin has been reported to induce
vivid dreams with intense colored visual imagery in normal
subjects and narcoleptic patients, it is suggested that enhanced
nocturnal melatonin secretion was associated with restoration of
dream recall in this patient. These findings demonstrate that
unlike chronic levodopa therapy, intermittent pulsed
applications of AC picotesla EMFs may induce in Parkinsonism
reactivation of reticular-limbic-pineal systems involved in the
generation of dreaming.
........
re: pineal calcification (PC)
[total calcification?]
Nocturnal plasma melatonin and alpha-melanocyte stimulating
hormone levels during exacerbation of multiple sclerosis.
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Sandyk R Awerbuch GI
INT J NEUROSCI 1992 Nov-Dec;67(1-4):173-86
The pineal gland has been implicated recently in the pathogenesis
of multiple sclerosis (MS). To investigate this hypothesis
further, we studied nocturnal plasma melatonin levels and the
presence or absence of pineal calcification (PC) on CT scan in a
cohort of 25 patients (5 men, 20 women; [....] PC was noted in
24 of 25 patients (96%) underscoring the pathogenetic relationship
between MS and the pineal gland. [....]